Technology with Articles

ProstaDrone®

The PROSTADRONE® Technology represents the next generation of prostate-oriented liposomal delivery platform in which the surface of the liposome is modified with layered with lycopene, providing passive, affinity-driven targeting and retention together with a built-in antioxidant shield. Because lycopene sits on the surface, the liposomal core is free to carry the active payload — CoQ10 or N-Acetyl Cysteine (NAC) — within one common carrier design.

Prostate health depends on getting the right nutrients into the right tissue. Taken by mouth, most nutrients are diluted across the body, degrade in the gut, or fail to enter prostate cells. ProstaDrone® is Nanotrition Nord’s answer: a patented target-organ delivery system that guides active nutrients to the prostate gland and its epithelium.

Why Conventional Prostate Supplements Fall Short?

Systemic dilution — oral delivery disperses nutrients across many organs, lowering their concentration in prostate tissue.
Limited tissue targeting — only a small fraction of an oral dose typically reaches the prostate.
Low cellular uptake — lipophilic actives such as CoQ10 and lycopene struggle to enter prostate epithelial cells and reach targets such as mitochondria.
Poor bioavailability — GI degradation cuts absorption; native lycopene is crystalline, poorly water-soluble and prone to oxidation.

How ProstaDrone® Works?

ProstaDrone® is a liposomal carrier with three engineered components:

COMPONENT	DESIGN	FUNCTION
Lycopene surface layer	Lycopene anchored on the outer liposomal surface via hydrophobic / lipid-affinity interactions	Passive affinity-based targeting and retention; direct antioxidant protection at the liposome–tissue interface; common to both payloads
Liposomal carrier	Phospholipid bilayer vesicle	Protects the payload through GI transit, supports absorption and sustained release
Core payload — CoQ10	INNOVA® CoQ10: ultra-pure (>98%), amorphous, thermostable, UV-resistant; in the lipid bilayer / lipophilic core	Mitochondrial respiratory support and ATP-synthesis in prostate epithelium
Core payload — NAC	Small, hydrophilic; positioned in the aqueous core; oxidation-protective processing (inert atmosphere, antioxidant excipients)	Glutathione-precursor-driven antioxidant defence

With lycopene on the surface, the liposomal core is free to carry an active payload — CoQ10 or NAC today, with further actives in the pipeline.

Mechanism of Action

Oral administration & GI absorption: the PEG coating protects the liposomal carrier during GI transit and supports systemic uptake.
Passive, affinity-driven recognition: the lycopene layer’s membrane and lipoprotein affinity drives accumulation and retention in lipid-rich prostate tissue.
Cellular uptake & retention: liposomes are taken up by prostate cells and retained, supporting sustained local action.
Payload release: the encapsulated CoQ10 or NAC is released inside the cell.
Local payload action: mitochondrial respiratory support and membrane antioxidant protection (CoQ10), or glutathione-driven antioxidant defence (NAC), with surface lycopene adding direct antioxidant action throughout.

Features & Benefits

3.74 X Prostate Affinity Using Passive, Lycopene-driven Affinity — simple surface chemistry with no peptide ligands.
Built-in surface antioxidant layer, independent of and in addition to the encapsulated payload.
Improved intracellular retention, supporting sustained local action of the delivered payload.
Smaller, more uniform, higher-loading liposomes (252.9 nm, PDI 0.283, EE 96.7%).
Good biocompatibility — cell survival >90% across 2.5–75 µg/mL.
Flexible core: CoQ10 or NAC inside the same lycopene-layered shell.

ProstaDrone® Product List

One validated delivery platform, a growing range of actives:

Product / active	Role	Position in carrier	Status
ProstaDrone® CoQ10	Mitochondrial respiratory & ATP support; antioxidant	Core (lipid bilayer)	Validated payload — in vitro, in vivo biodistribution, 28-day rat study
ProstaDrone® NAC	Glutathione precursor; antioxidant, anti-inflammatory support	Core (aqueous)	Validated payload — strong oral-NAC literature
ProstaDrone® Lycopene	Universal surface layer: passive targeting + antioxidant	Surface (affinity-coupled)	Platform component — liposomal affinity / antioxidant data (Li et al., 2025)
ProstaDrone® ALA	Alpha-lipoic acid — amphiphilic antioxidant	Core	Validated payload
ProstaDrone® Myo-Inositol	Metabolic / signalling support	Core (aqueous)	Validated payload
ProstaDrone® Saw Palmetto	Botanical for prostate and urinary comfort	Core (lipid)	Validated payload
…and more	Further antioxidant and mitochondrial-support actives	—	Contact us

Applications

Male reproductive health & prostate support — cellular energy metabolism (CoQ10), glutathione-driven antioxidant defence and semen-quality support (NAC), normal cellular function.
Prostate comfort & urinary health — targeted antioxidant and redox support in prostate tissue, relevant to prostatitis and benign prostatic hyperplasia (BPH) research.

Interested in ProstaDrone® for your formulation? Contact the Nanotrition Nord R&D team.